GUIDE TO LUPUS

SIGNS AND SYMPTOMS OF LUPUS

Each person with lupus has slightly different symptoms that can range from mild to severe and may come and go over time. However, some of the most common symptoms of lupus include painful or swollen joints (arthritis), unexplained fever, and extreme fatigue. A characteristic red skin rash (the so-called butterfly or malar rash) may appear across the nose and cheeks. Rashes may also occur on the face and ears, upper arms, shoulders, chest, and hands. Because many people with lupus are sensitive to sunlight (called photosensitivity), skins rashes often first develop or worsen after sun exposure.

Common Symptoms of Lupus

Painful or swollen joints and muscle pain
Unexplained fever
Red rashes, most commonly on the face
Chest pain upon deep breathing
Unusual loss of hair
Pale or purple of fingers from cold or stress (Raynaud's phenomenon)
Sensitivity to the sun
Swellling (edema) in legs or around eyes
Mouth ulcers
Swollen glands
Extreme fatigue

Symptoms of lupus can range from mild to severe and may come and go over time. Other symptoms of lupus include chest pain, hair loss, anemia ( a decrease in red blood cells), mouth ulcers, and pale or purple fingers and toes from cold stress. Some people also experience headaches, dizziness, depression, confusion, or seizures. New symptoms may continue to appear years after the initial diagnosis, and different symptoms can occur at different times. In some people with lupus, only one system of the body, such as the skin or joints, is affected. Other people experience symptoms in many parts of the their body. Just how seriously a body system is affected varies from person to person.

Systemic Effects

The following systems in the body can also be affected by lupus.

Kidneys: Inflammation of the kidneys (Nephritis) can impair their ability to get rid of waste products and other toxins from the body effectively. There is usually no pain associated with kidney involvement, although some patients may notice swelling in their ankles. Most often, the only indication of kidney disease is an abnormal urine or blood test. Because the kidneys are so important to overall health, lupus affecting the kidney generally requires intensive drug treatment to prevent further damage.

Lungs: Some people with lupus develop pleuritis, an inflamation of the lining of the chest cavity that causes chest pain, particularly with breathing. Patients with lupus may also get pneumonia.

Central nervous system: In some patients, lupus affects the brain or nervous system. This can cause headaches, dizziness, memory disturbances, vision problems, seizures, stroke, or changes in behavior.

Blood vessels: Blood vessels may become inflamed Vasculitis, affecting the way blood circulates through the body. The inflammation may be mild and may not require treatment or may be severe and require immediate attention.
Blood: People with lupus may develop anemia, leukopenia (a decreased number of white blood cells), or thrombocytopenia (a decrease in the number of platelets in the blood, which assist in clotting). Some people with lupus may have an increased risk for blood clots.

Heart: In some people with lupus, inflammation can occur in the heart itself )myocarditis and endocarditis) or the membrane that surrounds it pericarditis), causing chest pains other symptoms. Lupus can also increase the risk of atherosclerosis (hardening of the arteries).

Pregnancy for Women with Lupus

Although a lupus pregnancy is considered high risk, most women with lupus carry their babies safely to the end of their pregnancy. Women with lupus have a higher rate of miscarriage and premature births compared with the general population. In addition, women who have antiphosphollipid antibodies are at a greater risk of miscarriage in the second trimester because of their increased risk of blood clotting in the placenta. Lupus patients with a history of kidney disease have a higher risk of preeclampsia (hypertension with with a buildup of excess watery fluids in cells or tissues of the body). Pregnancy counseling and planning before pregnancy are important. Ideally, a woman should have no signs or symptoms of lupus and be taking no medications for at least 6 months before she becomes pregnant.

Some women may experience a mild to moderate flare during or after their pregnancy; others do not. Pregnant women with lupus, especially those taking corticosteriods, also are more likely to develop high blood pressure, diabetes, hypoglycemia (high blood sugar), and kidney complications, so regular care and good nutrition during pregnancy are essential. It is also advisable to have access to a neonatal (newborn) intensive care unit at the time of delivery in case the baby requires special medical attention.

Http://arthritis.about.com/od/lupus/a/guidetolupus 2.htm
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