Thursday, September 17, 2009

WHAT IS MULTIPLE SCLEROSIS?

WHAT IS UULTIPLE SCLEROSIS?
Multiple Sclerosis affects the central nervous system, comprised of the brain and spinal cord. In the CNS, nerve fibers or axons are surrounded by a layer of insulation called myelin. Myelin allows nerve signals to travel properly.
In MS, the myelin is destroyed (demyelination) on the brain and spinal cord. The scarring disrupts transmission of messages that communicate a desired action from the brain, through the spinal cord, to various parts of the body. The inflammation produced by MS damages the axons themselves and can cause permanent loss of function. The cells that produce myelin can also be damaged. This limits the ability of the brain to repair damaged myelin.
It is impossible to predict the severity or progression of any given individual. To better develop appropriate management plans, MS is divided into four classifications:’
Relapsing-Remitting-clearly defined attacks lasting from days to weeks, with full recovery or with some remaining neurological symptoms and deficits upon recovery. Periods between relapses are stable and absent of disease progression. This is by far the most common form of disease.
Secondary-Progressive-begins initially with a relapsing-remitting course that becomes consistently progressive. Deficits are accumulated without recovery between attacks.
Primary-Progressive-progression of level of disability from the onset without any distinct relapses of remissions. Temporary, minor improvements may be experienced.
Progressive-Relapsing-clear progression in disability level from the onset, but also clear acute relapses that may or may not include memory.

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